Is there a causal relationship between respiratory syncytial virus lower respiratory tract infection and chronic wheezing?

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RESPIRATORY INFECTION Seasonality of long term wheezing following respiratory syncytial virus lower respiratory tract infection

Background: It is well known that respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) is associated with subsequent wheezing episodes, but the precise natural course of wheezing following RSV LRTI is not known. This study aimed to determine the continuous development of wheezing following RSV LRTI in children up to the age of 3 years. Methods: A prospective cohort study w...

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Seasonality of long term wheezing following respiratory syncytial virus lower respiratory tract infection.

BACKGROUND It is well known that respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) is associated with subsequent wheezing episodes, but the precise natural course of wheezing following RSV LRTI is not known. This study aimed to determine the continuous development of wheezing following RSV LRTI in children up to the age of 3 years. METHODS A prospective cohort study w...

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Respiratory syncytial virus in lower respiratory tract infections.

Acute lower respiratory infections (ALRI) are a major cause of morbidity and mortality amongst children in developing countries. We evaluated the extent of respiratory syncytial virus (RSV) infection in children with ALRI using a rapid and sensitive enzyme immunoassay for the antigen detection directly from the nasopharngeal aspirate. The immune response to the virus was determined by detecting...

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Ribavirin for respiratory syncytial virus lower respiratory tract infection. A systematic overview.

OBJECTIVE To systematically review the evidence evaluating the efficacy of aerosolized ribavirin for the treatment of infants with respiratory syncytial virus lower respiratory tract infection. DESIGN A computerized search of MEDLINE from 1975 to the present, a review of the reference lists of each retrieved article, and contact with experts. PATIENTS infants with documented respiratory syn...

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Respiratory syncytial virus: co-infection and paediatric lower respiratory tract infections.

Comprehensive population-based data on the role of respiratory viruses in the development of lower respiratory tract infections (LRTIs) remain unclear. We investigated the incidence and effect of single and multiple infections with respiratory viruses on the risk of LRTIs in Vietnam. Population-based prospective surveillance and a case-control study of hospitalised paediatric patients with acut...

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ژورنال

عنوان ژورنال: The Lancet Respiratory Medicine

سال: 2020

ISSN: 2213-2600

DOI: 10.1016/s2213-2600(20)30118-1